ALS (Lou Gehrig’s Disease) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Daniela Zarnescu, associate professor at Molecular and Cellular Biology, and Alyssa Coyne, a graduate student in the UA’s Neuroscience Graduate Interdisciplinary Program, together with their colleagues, have identified a a clear molecular defect at the… Read More »
In humans, yeast and other eukaryotes, a group of proteins called the Target of Rapamycin Complex I (TORC1) promote cell growth and increase metabolic activity when nutrients are plentiful. Previous studies have shown how molecules that contain the nutrient nitrogen – which is needed to make proteins – activate TORC1. However, it is not clear… Read More »
Daniela Zarnescu, MCB associate professor, was awarded a research grant from the Muscular Dystrophy Association (MDA) totaling $300K over a period of three years to study metabolic dysregulation in people with amyotrophic lateral sclerosis (ALS). Congratulations Dr. Zarnescu!