Any link on the below references will take you off
of the BMCB site and to an abstract of that particular paper.
Yerushalmi, H.F., D.G. Besselsen, N.A. Ignatenko, K.A. Blohm-Mangone,
J.L. Padilla-Torres, D.E. Stringer, J.M. Guillen, H. Holubec, C.M.
Payne, and E.W. Gerner. 2006. Role of polyamines in arginine-dependent
colon carcinogenesis in Apc(Min) (/+) mice. Molecular Carcinogenesis (in press).
Bernstein, H., H. Holubec, C. Bernstein, N. Ignatenko, E. Gerner, K. Dvorak, D. Besselsen, L. Ramsey, M. Dall'agnol, K. Ann Blohm-Mangone, J. Padilla-Torres, H. Cui, H. Garewal, and C.M. Payne. 2006. Unique dietary-related mouse model of colitis. Inflammatory Bowel Diseases 12: 278-293.
Hariri, L.P., A.R. Tumlinson, D.G. Besselsen, U. Utzinger, E.W. Gerner, and J.K. Barton. 2006. Endoscopic optical coherence tomography and laser-induced fluorescence spectroscopy in a murine colon cancer model. Lasers in Surgery and Medicine 38: 305-313.
McNally, J.B., N.D. Kirkpatrick, L.P. Hariri, A.R. Tumlinson, D.G. Besselsen, E.W. Gerner, U. Utzinger, and J.K. Barton JK. 2006. Task-based imaging of colon cancer in the Apc(Min/+) mouse model. Applied Optics 45: 3049-3062.
Choi, W., L. Proctor, Q. Xia, Y. Feng, E.W. Gerner, P.J. Chiao,
S.R. Hamilton, and W. Zhang. 2006. Inactivation of IkappaB contributes
to transcriptional activation of spermidine/spermine N(1)-acetyltransferase. Molecular Carcinogenesis 45: 685-693.
Basuroy, U.K., and E.W. Gerner. 2006. Emerging concepts in targeting
the polyamine metabolic pathway in epithelial cancer chemoprevention
and chemotherapy. Journal
of Biochemistry (Tokyo) 139: 27-33.
Yerushalmi, H.F., D.G. Besselsen, N.A. Ignatenko, K.A. Blohm-Mangone,
J.L. Padilla-Torres, D.E. Stringer, H. Cui, H. Holubec, C.M. Payne,
and E.W. Gerner. 2006. The role of NO synthases in arginine-dependent
small intestinal and colonic carcinogenesis. Molecular
Carcinogenesis 45: 93-105.
Babbar, N., E.W. Gerner, and R.A. Casero Jr. 2006. Induction of
spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2
colon cancer cells. The
Biochemical Journal 394: 317-324.
Gerner, E.W., N.A. Ignatenko, P. Lance, and L.H. Hurley. 2005.
A comprehensive strategy to combat colon cancer targeting the adenomatous
polyposis coli tumor suppressor gene. Annals
of the New York Academy of Sciences 1059: 97-105.
Gerner, E.W. 2005. Changing winds in the war on cancer. Cancer
Biology and Therapy 4: 252-254.
Choi,W., E.W. Gerner, L. Ramdas, J. Dupart, J. Carew, L. Proctor,
P. Huang, W. Zhang, and S.R. Hamilton. 2005. Combination of 5-fluorouracil
and N1,N11-diethylnorspermine markedly activates spermidine/spermine
N1-acetyltransferase expression, depletes polyamines, and synergistically
induces apoptosis in colon carcinoma cells. Journal
of Biological Chemistry 280: 3295-3304.
Gerner, E.W., and R.L. Meyskens Jr. 2004. Polyamines and cancer:
old molecules, new understanding. Nature
Reviews. Cancer 4: 781-792.
Ignatenko, N.A., H. Zhang, G.S. Watts, B.A. Skovan, D.E. Stringer,
and E.W. Gerner. 2004. The chemopreventive agent alpha-difluoromethylornithine
blocks Ki-ras-dependent tumor formation and specific gene expression
in Caco-2 cells. Molecular
Carcinogenesis 39: 221-233.
Ignatenko, N.A., N. Babbar, D. Mehta, R.A. Casero Jr, and E.W.
Gerner. 2004. Suppression of polyamine catabolism by activated Ki-ras
in human colon cancer cells. Molecular
Carcinogenesis 39: 91-102.
Zaletok S, Alexandrova N, Berdynskykh N, Ignatenko N, Gogol S, Orlovsky O, Tregubova N, Gerner E, Chekhun V. Sep 2004. Role of polyamines in the function of nuclear transcription factor NF-kappaB in breast cancer cells. Experimental Oncology 26: 221-225.
Babbar, N., N.A. Ignatenko, R.A. Casero Jr, and E.W. Gerner. 2003.
Cyclooxygenase-independent induction of apoptosis by sulindac sulfone
is mediated by polyamines in colon cancer. Journal
of Biological Chemistry 278: 47762-47775.
Childs, A.C., D.J. Mehta, and E.W. Gerner. 2003. Polyamine-dependent
gene expression. Cellular
and Molecular Life Sciences 60: 1394-1406.
Gerner, E.W., N.A. Ignatenko, and D.G. Besselsen. 2003. Preclinical
models for chemoprevention of colon cancer. Recent
Results in Cancer Research 163: 58-71; discussion 264-266.
Ignatenko, N.A., and E.W. Gerner. 2003. Regulation of the HIV1
long terminal repeat by mutant heat shock factor. Experimental
Cell Research 288: 1-8.
Qu, N., N.A. Ignatenko, P. Yamauchi, D.E. Stringer, C. Levenson,
P. Shannon, S. Perrin, and E.W. Gerner. 2003. Inhibition of human
ornithine decarboxylase activity by enantiomers of difluoromethylornithine. The Biochemical Journal 375: 465-570.
Martinez, M.E., T.G. O'Brien, K.E. Fultz, N. Babbar, H. Yerushalmi,
N. Qu, Y. Guo, D. Boorman, J. Einspahr, D.S. Alberts, and E.W. Gerner.
2003. Pronounced reduction in adenoma recurrence associated with
aspirin use and a polymorphism in the ornithine decarboxylase gene. Proceedings of the National Academy of Sciences U.S.A. 100: 7859-7864.
Husbeck, B., D.E. Stringer, E.W. Gerner, and G. Powis. 2003. Increased
thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer
cells. Biochemical
and Biophysical Research Communications 306: 469-475.
Babbar, N., and E.W. Gerner. 2003. Polyamines as modifiers of genetic
risk factors in human intestinal cancers. Biochemical
Society Transactions 31: 388-392.
Parker, M.T., and E.W. Gerner. 2002. Polyamine-mediated post-transcriptional
regulation of COX-2. Biochimie 84: 815-819.
Baines, A., M. Taylor-Parker, A.C. Goulet, C. Renaud, E.W. Gerner,
and M.A. Nelson. 2002. Selenomethionine inhibits growth and suppresses
cyclooxygenase-2 (COX-2) protein expression in human colon cancer
cell lines. Cancer
Biology and Therary 1: 370-374.
Fultz, K.E., and E.W. Gerner. 2002. APC-dependent regulation of
ornithine decarboxylase in human colon tumor cells. Molecular
Carcinogenesis 34: 10-18.
Quinones, H.I., A.F. List, and E.W. Gerner. 2002. Selective exclusion
by the polyamine transporter as a mechanism for differential radioprotection
of amifostine derivatives. Clinical
Cancer Research 8: 1295-1300.
Lawson, K.R., S. Marek, J.A. Linehan, P.M. Woster, R.A. Casero
Jr, C.M. Payne, and E.W. Gerner. 2002. Detoxification of the polyamine
analogue N1-ethyl-N11-[(cycloheptyl)methy]-4,8-diazaundecane (CHENSpm)
by polyamine oxidase. Clinical
Cancer Research 8: 1241-1247.
Elmore, E., D.E. Stringer, V.E. Steele, E.W. Gerner, and J.L. Redpath.
2001. Chemoprevention by difluoromethylornithine: correlation of
an in vitro human cell assay with human clinical data for biomarker
modulation. Anticancer
Research 21: 1163-1165.
Simoneau, A.R., E.W. Gerner, M. Phung, C.E. McLaren, and F.L. Meyskens
Jr. 2001. Alpha-difluoromethylornithine and polyamine levels in
the human prostate: results of a phase IIa trial. Journal of
the National Cancer Institute 93: 57-59.
