Justina McEvoy - Assistant Professor
We study the regulation of differentiation programs during normal development and tumorigenesis in pediatric cancers; focusing on two projects. The first project studies the role of the Rb tumor suppressor in regulation of differentiation pathways in a rare childhood cancer of the retina called retinoblastoma. The second project studies the relationship between the genetic and epigenetic contributions in a pediatric cancer called rhabdomyosarcoma. Overall, we hope to shed light on the underlying biological mechanisms of normal development and tumorigenesis and provide novel therapeutic approaches for these devastating pediatric cancers.