Event
Location
Stevie Eller Dance Theater
When
12:01 a.m. March 9, 2020 to 11:59 p.m. March 13, 2020
Presenter: Carol Dieckmann, Professor, Molecular and Cellular Biology, University of Arizona
We work with a single-celled green algae similar to pond scum, called Chlamydomonas. Like plants, Chlamydomonas cells make energy from sunlight. The highly organized structure inside the cell called the eyespot contains molecules that sense light. We study the eyespot as a model for understanding how cells establish up, down, left, right, and the 3D location of unique internal compartments. Assembling and placing structures accurately is important for the health of all cells/organisms. Understanding the fundamentals of cell biology is vital to understanding human biology.
When
6:30 p.m. to 8 p.m. Dec. 5, 2019
Location
SaddleBrooke DesertView Performing Arts Center:39900 S Clubhouse Dr, Tucson, AZ 85739
Title: "Taking out the Trash: Migratory Neural Crest Cells Phagocytose Dead Cells in the Developing Nervous System"
Contact: Ross Buchan
When
11 a.m. to 12:15 p.m. Oct. 31, 2019
Location
ENR2, Rm S215
"Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas.”
Paper: Dolan AE, et al., Mol Cell. 2019 Jun 6;74(5):936-950.
Contact: Tim Bolger
When
11 a.m. to 12:15 p.m. Oct. 3, 2019
Location
ENR2, Room S107
Cancer is the second most common cause of death in the US – yet progress is being made in understanding this disease and developing cures. We will discuss our understanding of the types, causes and drivers of cancer, with a focus on metastatic disease. We will then turn to some recent breakthroughs, including immunotherapy. Finally, we will discuss those cancers for which therapies do not work, and discuss new research underway that is designed to understand the causes of cancer resistance and relapse.
Location
SaddleBrooke DesertView Performing Arts Center:39900 S Clubhouse Dr, Tucson, AZ 85739
Fruit flies can be annoying little flyers buzzing around your kitchen table when you forget those bananas out! But what you may not know about the tiny fruit fly is that for over 100 years it has been a workhorse for understanding fundamental facts about human biology and disease. Like humans, fruit flies have a brain, can learn, sleep, drink and get addicted, and are providing a great model for studying age and age-related neurodegenerative disorders. They have even helped discover drug therapies for cancer! We will cover the history of major genetic discoveries that led to several Nobel prizes and discuss some of the ways in which flies can help us understand disease mechanisms and develop therapies for humans in a “fly-to-man” approach.
Location
SaddleBrooke DesertView Performing Arts Center:39900 S Clubhouse Dr, Tucson, AZ 85739
Chlamydomonas are single-celled green algae similar to pond scum. Like plants, Chlamydomonas cells make energy from sunlight. They swim toward light using a pair of whip-like flagella that breaststroke through the water. Swimming direction is determined by a highly organized structure inside the cell called the eyespot. Like human eyes, the eyespot contains molecules that sense light. To form the eyespot, the light sensors assemble with Velcro-like helper proteins at a precise position relative to the flagella. We study the eyespot as a model for understanding how cells establish up, down, left, right, and the 3D location of unique internal compartments. Assembling and placing structures accurately is important for the health of all cells/organisms. To examine how the eyespot forms at the correct location in the cell, we label different proteins with glow-in-the-dark colors and take pictures with a high-powered microscope. The “skeleton” of the cell and the flagella are labeled green. The light-sensing proteins in the eyespot are red. The MLT1 protein, identified in our lab, is blue. MLT1 is a very large protein that helps direct the light-sensing proteins to the eyespot.
Location
SaddleBrooke DesertView Performing Arts Center:39900 S Clubhouse Dr, Tucson, AZ 85739
Hosted by Department Staff
When
2:30 p.m. to 3:30 p.m. Sept. 11, 2019
Location
Life Sciences South, 4th Floor Lobby
