Lisa Nagy : This image shows an 8-cell stage of the mud snail Ilyanassa obsoleta embryo that was treated with a chemical antagonist of the NMDA receptor. This treatment disrupts the correct spindle orientation and pPKC localization, suggesting that NMDA receptor signaling is required for cell polarization during the early asymmetric cleavages of the mud snail. Nuclei (blue) are stained with DAPI, microtubules (green) and phosphorylated protein kinase C (pPKC) (red) are stained with their specific antibodies. Lisa Nagy: This image shows an 8-cell stage of the mud snail Ilyanassa obsoleta embryo that was treated with a chemical antagonist of the NMDA receptor. This treatment disrupts the correct spindle orientation and pPKC localization, suggesting that NMDA receptor signaling is required for cell polarization during the early asymmetric cleavages of the mud snail. Nuclei (blue) are stained with DAPI, microtubules (green) and phosphorylated protein kinase C (pPKC) (red) are stained with their specific antibodies.

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